INNOVATIVE BIOPHYSICAL TECHNOLOGIES
A. DERMATOLOGY RESEARCH ACHIEVEMENTS - Stanford University Medical School
PSORIASIS RESEARCH
- Developed method for long-term maintainance of human skin mast cells in tissue culture
- Demonstrated effects of neuropeptides on human skin mast cells
- First time characterization of the sodium-hydrogen antiporter in human keratinocytes
- Developed new psycho-neuroimmunology model explaining effects of mental & emotional states on skin physiology
B. SKIN BIOLOGY RESEARCH - Estee Lauder R&D
I. ESSENTIAL OILS
- First time characterization of physiological effects of topical essential oils on human skin
Anti-oxidant
Anti-inflammatory
Modulatory effects on specific biochemical pathways
- First time characterization of sensory effects of topical essential oils on human skin
Heating
Cooling
Tingling
- Clinical evaluation of essential oils blends to affect novel mental and emotional states of consciousness
Trustworthiness
Happiness
Sociability
- Developed novel platform for formulators describing physiological and psychological effects of essential oils
II. ELECTROMAGNETIC FIELDS
a. CLINICAL
- Measured endogenous DC electric fields in normal and wrinkled skin
- First time characterization of the effects of external DC electric fields on wrinkles
- Measured the pulsed electromagnetic fields emitted by human skin
- Developed new biophysical method for measuring charge distribution on skin surface
- Characterized the effects of topical cosmetic products on charge distribution on skin surface
b. IN-VITRO
- Investigated the effects of external electromagnetic fields on human keratinocytes
- Characterized the effects of visible light on biochemical pathways in human keratinocytes
anti-oxidant activity
anti-inflammatory role of interleukins
melatonin
C. MODELLING
- Co-developed a comprehensive model of skin aging based on a micro- inflammatory cycle
- Published the model in 2001
- Invited to update and republished the model in 2012